Medical-Vaccines, Trials & Other Treatments

I know we have read that a vaccine might be available in 3 months. This report says it could take longer ... much longer.

 Hat Tip to John West's Daily Big Threat Blot:

A vaccine for Wuhan coronavirus could take years to develop, based on our experience trying to fight Zika and Ebola
https://www.businessinsider.com/how-long-to-make-vaccine-for-wuhan-china-coronavirus-timeline-2020-1

SNIPS:
. . . Several biotech companies have rolled out plans to develop vaccines to protect people against the Wuhan, China coronavirus, with support from global health groups and the US government.

. . . But vaccine development has historically been an arduous, multi-year process. None of the biotechs provided expected timelines to get their vaccines on the market.

. . . Previous infectious disease outbreaks, including for the Ebola and Zika viruses, show the challenges likely to face experimental vaccines for this virus as well.

. . . Anthony Fauci, the longtime director of the NIH's National Institute of Allergy and Infectious Diseases, estimated the first clinical trials for a coronavirus vaccine could begin before this summer, in an interview with the industry publication Biocentury.

 Hat Tip to John West's Daily Big Threat Blog:

Scientists are moving at record speed to create new coronavirus vaccines—but they may come too late
https://www.sciencemag.org/news/2020/01/scientists-are-moving-record-speed-create-new-coronavirus-vaccines-they-may-come-too

(SNIP) ... with infections of a novel coronavirus exploding in China—case numbers soared to over 2700 the past 24 hours—and racing around the world, scientists contend they are better prepared than ever to produce a vaccine at Hollywood speed. Of course, the 2019-novel coronavirus (2019-nCoV), as it is now dubbed, has a solid lead in the race, and by the time a vaccine proves its worth in a clinical trial and manufacturers scale up production, it once again may be too late to make a significant dent in the course of the epidemic. But scientists hope they can make a difference.

ReadyMom wrote:  Hat Tip to John West's Daily Big Threat Blog:

Scientists are moving at record speed to create new coronavirus vaccines—but they may come too late
https://www.sciencemag.org/news/2020/01/scientists-are-moving-record-speed-create-new-coronavirus-vaccines-they-may-come-too

(SNIP) ... with infections of a novel coronavirus exploding in China—case numbers soared to over 2700 the past 24 hours—and racing around the world, scientists contend they are better prepared than ever to produce a vaccine at Hollywood speed. Of course, the 2019-novel coronavirus (2019-nCoV), as it is now dubbed, has a solid lead in the race, and by the time a vaccine proves its worth in a clinical trial and manufacturers scale up production, it once again may be too late to make a significant dent in the course of the epidemic. But scientists hope they can make a difference.

   https://www.fda.gov/media/133748/download


I'm not sure we want a vaccine "rushed to market"   I guess they could test in in China where things are already out of control but ...   So many questions.  Would it shed the virus?  Look at an Ebola vaccine insert and it says (page 7)
"Shedding
Shedding of vaccine virus into the urine or saliva was evaluated in 299 subjects enrolled in seven
clinical studies who were vaccinated with ERVEBO or lower dose formulations. Vaccine virus RNA wasdetected by RT-PCR in the urine or saliva of some subjects at timepoints ranging from Day 1 through Day 14 postvaccination. In the two studies that assessed shedding at Day 28, no samples tested positive.
Vaccine virus RNA was detected by RT-PCR in vesicular fluid samples from some subjects. In one subject, a sample collected 20 days after vaccination tested positive for vaccine virus RNA by RT-PCR.       If the virus sheds can it give a false sense of security to use it in a population that does not have virus cases yet ... even cause some spread?

Hat Tip to John West's Daily Big Threat Blog:

China To Begin Testing Ebola Drug on Coronavirus Patients
http://www.sixthtone.com/news/1005155/china-to-begin-testing-ebola-drug-on-coronavirus-patients

China has announced it will immediately commence clinical trials on an experimental drug, remdesivir, in hopes of finding an effective treatment for the novel coronavirus that has killed over 360 people and infected another 17,000 since mid-December.

The trial, which begins Monday and runs through April 27, will take place in the central city of Wuhan and include a total of 270 novel coronavirus patients, ---CONTINUED---

ReadyMom wrote:  Hat Tip to John West's Daily Big Threat Blog:

China To Begin Testing Ebola Drug on Coronavirus Patients
...
The trial, which begins Monday and runs through April 27, will take place in the central city of Wuhan and include a total of 270 novel coronavirus patients,   ---CONTINUED---

OK, looks like we have a 50/50 shot at an antiviral.
If we can wait until 27Apr.

Anyone want to guess how many cases there will be by then?

Remember: preppers are crazy, nothing like this could possibly happen.

Hat Tip to 'Treyfish', FluTrackers:

Some People are Recovering From Coronavirus in 2 Days With Flu and HIV Drugs
https://nextshark.com/thailand-coronavirus-treatment/

Thailand has reported promising results in the treatment of the 2019 novel coronavirus (2019-nCoV) on Sunday.

According to the kingdom’s health ministry, a 71-year-old female patient — a Chinese national — tested negative for the pathogen 48 hours after doctors administered a combination of antiviral drugs..


Doctors combined lopinavir and ritonavir, medications used for managing HIV, with oseltamivir, a drug for treating influenza. They are currently waiting for research results to confirm the findings.

“The lab result of the positive on the coronavirus turned negative in 48 hours,” Dr. Kriengsak Attipornwanich said, according to AFP. “From being exhausted before, she [patient] could sit up in bed 12 hours later.”: ---CONTINUED---

Hat Tip to John West's Daily Big Threat Blog:

China speeds up clinical trials of effective therapies against virus
https://www.plenglish.com/index.php?o=rn&id=51831&SEO=china-speeds-up-clinical-trials-of-effective-therapies-against-virus

Beijing, Feb 5 (Prensa Latina) China has accelerated the clinical trials of medicines and methods that had positive results in some infected with the 2019 nCoV in order to reach the stage of their distribution, all the while continuing the search for a truly effective vaccine.

According to the National Health Committee, there was an improvement on the patients' state after applying antivirals along with traditional medicine products, western medicine, and equipment such as respirators, blood filters and the so-called artificial lungs, especially in patients in a severe state. ---continued---

Hat Tip to John West's Daily Big Threat Blog:

Chinese researcher says two new drugs may help treat coronavirus
https://www.pharmaceutical-technology.com/news/china-new-coronavirus-drugs/

A research team at Zhejiang University in China have found that two drugs, Abidol and Darunavir, may help treat patients infected with the new coronavirus, reported Changjiang Daily.

Preliminary in-vitro testing showed the drugs to be effective in blocking the virus. ---CONTINUED---

ReadyMom wrote:...
Thailand has reported promising results in the treatment of the 2019 novel coronavirus (2019-nCoV) on Sunday.

According to the kingdom’s health ministry, a 71-year-old female patient — a Chinese national — tested negative for the pathogen 48 hours after doctors administered ...

Just for the record, testing negative isn't "cured"
it is "remission"
I find it disturbing that medical people would blur the distinction.

 Hat Tip to John West's Daily Big Threat Blog:

Coronavirus vaccine could be tested on animals 'next week'
https://uk.style.yahoo.com/coronavirus-vaccine-could-be-tested-on-animals-next-week-142902736.html

(SNIP) ... Scientists from Imperial College London claim, however, they are well on the way to developing a vaccine against the infection.

Animal studies could be initiated as soon as next week, with human trials taking place within the next few months if funding is secured, they add.

The BBC previously reported scientists started working on a jab within hours of the coronavirus being identified.   ---CONTINUED---

If coronavirus virus or any pandemic hits your area, here are some preventions/precautions that should be taken, from Happy Preppers:


https://www.happypreppers.com/coronavirus.html

Hat Tip to 'Zac', FluTrackers:

TRANSLATION:

Ribavirin, penciclovir, nitazoxanide, nafamostat, chloroquine, remdesivir and favipiravir tested against 2019-nCoV in vitro
https://translate.google.com/translate?hl=en&sl=zh-CN&u=https://www.huxiu.com/article/338151.html&prev=search

Today, 11:11 AM

Chinese team finds drugs effectively inhibit new coronavirus in vitro [cell culture, not in animal]

...they evaluated five FDA-approved drugs, ribavirin, penciclovir, nitazoxanide, nafamostat and chloroquine, and two The efficacy of a well-known broad-spectrum antiviral drug, remdesivir (GS-5734) and favipiravir (T-705), against 2019-nCoV in vitro.

Nitazoxanide is an antiprotozoal drug that has the potential to combat a wide range of viruses, including human and animal coronaviruses, and inhibits 2019-nCoV at low micromolar concentrations (EC 50 = 2.12 μM) . It is recommended to further evaluate the effectiveness of the drug in vivo against 2019-nCoV infection. [Comment: repeated 500 mg BID administration yields 9 μM blood serum concentration, Kucers' Antibiotic reference. Nitazoxanide also has immunomodulary and anti-inflammatory properties and studies found 500 mg BID for 5 days had side effects similar to placebo.

It is worth noting that two compounds, remdesivir and chloroquine, can effectively block 2019-nCoV infection at micromolar concentrations, with EC 50 values ​​of 0.77 μM and 1.13 μM, respectively; the selectivity index of the two is used to judge the drug effect (The larger the index, the larger the safety range) are (Figure 1a, b) .

Remdesivir has recently been recognized as a promising antiviral drug that can fight multiple RNA virus (including SARS / MERS-CoV) infections in cultured cells, mice and non-human primate models. The drug is currently undergoing clinical research to treat Ebola virus infection. Remdesivir is an adenosine analog that integrates into the nascent viral RNA strand, leading to the termination of pre-mature. This new study found that remdesivir works after the virus enters the cells (Figure 1c, d) , consistent with its well-known antiviral mechanism as a nucleotide analog. In addition, preliminary data show that remdesivir can also effectively inhibit human cell lines sensitive to 2019-nCoV.

Chloroquine is a widely used antimalarial and autoimmune disease drug and has recently been reported as a potential broad-spectrum antiviral drug. Chloroquine is known to prevent viral infections by increasing the endosome pH required for virus / cell fusion and interfering with the glycosylation of SARS-CoV cell receptors. This new study confirms that Chloroquine plays a role during the virus invasion phase and after virus invasion of Vero E6 cells infected with 2019-nCoV (Figure 1c , d) . In addition to its antiviral effect, Chloroquine also has an immunomodulatory effect, which can synergistically enhance its antiviral effect in vivo. Chloroquine is widely distributed throughout the body, including the lungs, after oral administration. The EC 90 value of 2019-nCoV in Chloroquine anti-Vero E6 cells is 6.90 μM, which is clinically achievable, which was confirmed in the plasma of patients with rheumatoid arthritis administered 500 mg. Chloroquine is a cheap and safe drug that has been used for more than 70 years, so it may be clinically applicable to 2019-nCoV. [Comment: chloroquine has narrow therapeutic range and less than benign side effect profile

In summary, the study shows that remdesivir and chloroquine are effective in controlling 2019-nCoV infection in vitro. Because these compounds have been used in patients with safety records and have proven effective against a variety of diseases, researchers have suggested that the two drugs should be evaluated in patients infected with the new coronavirus.

Hat Tip to John West's Daily Big Threat Blog:

Colombia makes 1st coronavirus test in Latin America
https://newsus.cgtn.com/news/2020-02-08/Colombia-makes-1st-coronavirus-test-in-Latin-America-NU8bsAbFlu/index.html

Colombia's National Health Institute has developed the first coronavirus diagnostic test in Latin America.

The test allows potential victims to be diagnosed in less than eight hours.

It was developed in one of the 12 laboratories of Colombia's National Health Institute.

This means Colombia will no longer have to send samples to the United States to confirm a coronavirus infection.

The South American nation is now offering support to other countries in the region. ---CONTINUED---

ReadyMom wrote:  Hat Tip to John West's Daily Big Threat Blog:
Colombia makes 1st coronavirus test in Latin America
https://newsus.cgtn.com/news/2020-02-08/Colombia-makes-1st-coronavirus-test-in-Latin-America-NU8bsAbFlu/index.html
Colombia's National Health Institute has developed the first coronavirus diagnostic test in Latin America.
The test allows potential victims to be diagnosed in less than eight hours.
It was developed in one of the 12 laboratories of Colombia's National Health Institute.
This means Colombia will no longer have to send samples to the United States to confirm a coronavirus infection.
The South American nation is now offering support to other countries in the region.   ---CONTINUED---

The only things they don't tell is the cost (a critical factor) and accuracy.

Other than that, this is great news. If the test is accurate before the person begins to spread the virus, that means quarantines will become effective tools, rather than the "screen door in driving rainstorm" level of effectiveness.

Hat Tip to FluWiki, Facebook:

Antiviral drug, Remdesivir, being used for treatment of novel coronavirus
http://outbreaknewstoday.com/antiviral-drug-remdesivir-being-used-for-treatment-of-novel-coronavirus-55301/?fbclid=IwAR3SYZHtqzHQ69fycBh2I8r1sLYQ89DHVaaibJ30OLGIRo2zkduK1cOaN-g

The investigational drug remdesivir, developed through research conducted through the Antiviral Drug Discovery and Development Center, or AD3C, and centered at the University of Alabama at Birmingham, is being used to treat select infected patients in the United States and in China who have been affected by the outbreak of novel coronavirus (2019-nCoV). ---continued---

Andrew W Saul, Facebook

Vitamin C Infusion for the Treatment of Severe 2019-nCoV Infected Pneumonia
https://clinicaltrials.gov/ct2/show/NCT04264533

China is conducting a clinical trial of 24,000 mg/day of intravenous vitamin C for coronavirus patients. They will receive it for 7 days straight at Zhongnan Hospital of Wuhan University.

Hat Tip to FluWiki, Facebook:

Vaccine for new coronavirus could be ready in 18 months: WHO
https://news.cgtn.com/news/2020-01-25/Expert-Drugs-to-be-used-for-treatment-of-new-coronavirus-NxlcvKmiWs/index.html

Several kinds of drugs will be used for clinical treatment of the novel coronavirus, said Zhong Nanshan, a respiratory expert now leading the panel on the outbreak for China's National Health Commission, adding that the safety of the drugs have been ensured, but their efficacy still need to be further confirmed. ---CONTINUED---

Hat Tip to John West's Daily Big Threat Blog:

There's No Specific Drug That Kills Coronavirus. But Doctors Have Ways To Treat It
https://www.npr.org/sections/goatsandsoda/2020/02/11/804862868/theres-no-specific-drug-that-kill-coronavirus-but-doctors-have-ways-to-treat-it

Even though the coronavirus disease that has sickened tens of thousands of people in China is new to science, doctors have a pretty good idea about how to treat it. COVID-19, as it is now named, attacks the lungs. Doctors see similar symptoms from other diseases all the time, especially from serious cases of the flu.

There's no specific drug that can kill this virus. So doctors provide what's known as supportive care, says Dr. Laura Evans, a critical care specialist at the University of Washington and a member of the Society of Critical Care Medicine's Leadership Council. ---CONTINUED---

Hat Tip to Avian Flu Diary

Problematic Lab Testing For The Novel Coronavirus
https://afludiary.blogspot.com/2020/02/problematic-lab-testing-for-novel.html

For several weeks there have been murmurs - first in Chinese social media - and more recently from more official sources, that the lab tests being used to detect the novel coronavirus in China - and elsewhere - aren't as sensitive as we'd hope.

Patients - even those with overt symptoms - sometimes test negative, even though they are actually infected.

This isn't a new problem, and we've seen it in the past with avian flu (H5N1 in particular), and with MERS-CoV. Nearly two weeks ago, on February 1st, I wrote: ---CONTINUED---

Hat Tip to Avian Flu Diary

China To Try Convalescent Plasma Therapy (Again) Against Coronavirus
https://afludiary.blogspot.com/2020/02/china-to-try-convalescent-plasma.html

(SNIP) ... A therapy for the novel coronavirus that involves the plasma of recovered patients has started to show effects, according to Zhang Dingyu, president of Jinyintan Hospital in Wuhan, Hubei province, a major battleground for the outbreak.

The plasma contains large volumes of antibodies for the deadly pathogen, Zhang told a daily news conference late on Thursday.

He pleaded to recovered patients to donate blood to the benefit of all. ---CONTINUED---

ReadyMom wrote: Hat Tip to Avian Flu Diary

China To Try Convalescent Plasma Therapy (Again) Against Coronavirus
https://afludiary.blogspot.com/2020/02/china-to-try-convalescent-plasma.html

RELATED:

Hat Tip to John West's Daily Big Threat Blog:

Chinese Doctors have Found a Way to Treat Coronavirus-Infected People
https://www.novinite.com/articles/203164/Chinese+Doctors+have+Found+a+Way+to+Treat+Coronavirus-Infected+People

China's technique for plasma transfusion from cured coronavirus to infected patients has proven to be effective, Xinhua News Agency reported, citing local doctors.

The effectiveness of the new treatment was announced at a press conference by the Wuhan hospital manager.

China National Biotec Group said it has collected plasma from some recovered patients to prepare therapeutic products including convalescent plasma and immune globulin. ---CONTINUED---

Hat Tip to FluWiki, Facebook:

Clinical evidence suggests antimalarial drug is effective on COVID-19 patients
https://news.cgtn.com/news/2020-02-17/Antimalarial-drug-proves-effective-on-COVID-19-patients--OabJzjgaZ2/index.html?fbclid=IwAR37OOnrXUcndZeKidK_PcGYmf3AC6WOOo7GaDJ3SCERU8qyfDqasbwmr7k

Chloroquine phosphate, an antimalarial drug that has been on the market for many years, has proved to be effective against the novel coronavirus, according to Sun Yanrong, deputy director of the biological center under China's Ministry of Science and Technology (MST).

Sun said that the clinical evidence from over 10 hospitals in Beijing, Guangzhou and Hunan Province shows the cure rate of patients who are negative in nucleic acid tests after treatment with the antimalarial drug is higher than in the controlled group. "Over 100 patients have shown no signs of side effects," she added. ---CONTINUED---

Hat Tip to John West's Daily Big Threat Blog:

China approves flu drug being touted as a potential coronavirus treatment amid a rush of clinical studies
https://endpts.com/china-approves-flu-drug-being-touted-as-a-potential-coronavirus-treatment-amid-a-rush-of-clinical-studies/

One of the three drugs that China’s Ministry of Science and Technology has tapped as potential COVID-19 treatments to watch has notched its first Chinese OK — for the flu.

While there’s no proof yet that fapilavir, or favipiravir, is the cure that patients and physicians are yearning for, it stands out for a unique constellation of qualities. It’s been commercially available in Japan for several years (unlike Gilead’s experimental remdesivir) yet it’s new to China (unlike the malaria drug chloroquine phosphate). Perhaps more importantly, a domestic biotech — Zhejiang Hisun Pharma — owns the rights to manufacture and market the drug, preempting any concerns about patents. ---CONTINUED---

From 13 hours ago, possible vaccine/cure for coronavirus, drug name and company that makes it:

https://www.clinicaltrialsarena.com/analysis/coronavirus-mers-cov-drugs/

We knew this already:

Hat Tip to FluWiki, Facebook:

Coronavirus vaccine could take up to 12-18 months, says WHO
https://www.independent.ie/world-news/coronavirus-vaccine-could-take-up-to-12-18-months-says-who-38968825.html

A vaccine against coronavirus could take more than a year to develop, the World Health Organisation (WHO) has said.

Addressing a press conference in Geneva, Switzerland, director-general Dr Tedros Adhanom Ghebreyesus said that preparing a vaccine was planning for the "worst situation".

(SNIP) ... He said that development would be costly, warning that funds "cannot and should not" be pulled away from helping weaker health systems prepare for the coronavirus, also known as Covid-19. ---CONTINUED---

Hat Tip to FluWiki, Facebook:

Scientists map the part of the coronavirus that lets it infect human cells - and say their discovery could be the key to a vaccine in under two years
https://www.dailymail.co.uk/health/article-8021285/Texas-scientists-say-discovery-lead-coronavirus-vaccine.html

-University of Texas at Austin scientists have created the first 3D map of the protein 'spike' on the coronavirus's exterior that lets it invade human cells
-In order to do so, they had to recreate a version of the protein itself
-The molecule they created can serve as a vaccine against the virus
-In collaboration with the NIH and Moderna Therapeutics, the scientists are now working to develop a vaccine based on their discovery
-Trials in humans could begin in a matter of months, but the shot wouldn't be ready for 18 months to two years, the team says ---CONTINUED---

Hat Tip to John West's Daily Big Threat Blog:

Trials to Test Ebola Drug's Potential to Prevent, Treat Coronavirus
https://www.voanews.com/science-health/coronavirus-outbreak/trials-test-ebola-drugs-potential-prevent-treat-coronavirus

An American biotech company says it is working with Chinese authorities to determine whether the antiviral drug remdesivir may provide an effective treatment for victims of the fast-spreading coronavirus known as COVID-19. The Chinese researchers hope to have the answer by May 1.

Officials of Gilead Sciences, which invented remdesivir as a treatment for Ebola and another disease, told VOA the company has initiated two clinical trials among infected patients "to determine the safety and efficacy of remdesivir as a potential treatment for the coronavirus." ---CONTINUED---

[ Hat Tip to FluWiki, Facebook:

b]New COVID-19 drugs approved for fast and accurate diagnosis: China's top epidemiologist [/b]
https://www.globaltimes.cn/content/1180544.shtml

China's National Medical Product Administration has issued approvals for several types of drugs that are effective for diagnosing novel coronavirus pneumonia or COVID-19, the country's top epidemiologist and leading government medical adviser Zhong Nanshan announced on Sunday.

Zhong shared the news on Sunday afternoon during a video conference while conducting a special medical consultation with doctors in Jingzhou, Central China's Hubei Province and medics from South China's Guangdong Province who were sent to help. ---CONTINUED---

Antibody test kits for rapid novel coronavirus detection approved in China
http://www.ecns.cn/news/2020-02-25/detail-ifztvsqr0581222.shtml

he National Medical Products Administration (NMPA) has approved two antibody test kits for the rapid detection of novel coronavirus infections.

According to the NMPA official website, it has fast-tracked three test kits for novel coronavirus infections, including two antibody test kits and one nucleic acid kit. ---CONTINUED---

Hat Tip to FluWiki, Facebook:

U.S. FDA official warns of possibility of coronavirus pandemic
https://www.reuters.com/article/us-china-health-usa-fda-idUSKCN20K2QO

(SNIP) ... Speaking earlier at the conference, Marks said that three-month estimates for a coronavirus vaccine to enter human trials may be too aggressive.

“We’re hoping in next quarter or two there will be a vaccine that will be ready to move” into human trials, he said.

ReadyMom wrote:...
(SNIP) ... Speaking earlier at the conference, Marks said that three-month estimates for a coronavirus vaccine to enter human trials may be too aggressive.
...

There are risks associated with any vaccine, and despite the dangers this virus presents, we don't want to make it worse by using a vaccine that might start it into mutations.

This has been a problem with using flu vaccines in swine and bird populations, the flu simply mutates to get around the vaccine.

Hat Tip to FluWiki, Facebook:

China puts 245 COVID-19 patients on plasma therapy, yielding positive results
http://en.people.cn/n3/2020/0228/c90000-9663191.html?fbclid=IwAR3-NC9Eqi1GnnBEKfyo_3TDLL6DfMwreUhWfubwLMiEPT_WROOuSOuRzaQ

BEIJING, Feb. 28 (Xinhua) -- China has offered plasma therapy for 245 COVID-19 patients by Friday, and 91 cases have shown improvement in clinical indicators and symptoms, a health official said Friday.

Up to 544 doses of plasma from convalescent COVID-19 patients have been collected across the country for treatment, said Guo Yanhong, an official with the National Health Commission (NHC) at a press conference Friday.

The plasma therapy has proved safe and effective, Guo added. ---continued---

Hat Tip to FluWiki, Facebook:

Coronavirus: Scientists stumble on potential vaccine by 'pure luck'
https://www.newshub.co.nz/home/world/2020/02/coronavirus-scientists-stumble-on-potential-vaccine-by-pure-luck.html

Scientists in Israel say they're very close to producing a vaccine for COVID-19, the deadly coronavirus which is sweeping the world.

(SNIP) ... Science and Technology Minister Ofir Akunis on Thursday (Israel time) said they were just a few weeks away from having it ready.

"I am confident there will be further rapid progress, enabling us to provide a needed response to the grave global COVID-19 threat," he said, The Jerusalem Post reported.

The potential vaccine is being developed at the Galilee Research Institute. Prime Minister Benjamin Netanyahu ordered scientists to work on a vaccine in the first week of February, the Times of Israel reported.

The scientists stumbled upon the potential vaccine by "pure luck", biotechnologist Chen Katz told The Jerusalem Post. ---continued---

Israeli scientists: 'In a few weeks, we will have coronavirus vaccine'
https://www.jpost.com/HEALTH-SCIENCE/Israeli-scientists-In-three-weeks-we-will-have-coronavirus-vaccine-619101

Once the vaccine is developed, it will take at least 90 days to complete the regulatory process and potentially more to enter the marketplace.

Israeli scientists are on the cusp of developing the first vaccine against the novel coronavirus, according to Science and Technology Minister Ofir Akunis. If all goes as planned, the vaccine could be ready within a few weeks and available in 90 days, according to a release. ---CONTINUED---

Hat Tip to John West's Daily Big Threat Blog:

Global Trials Soon to Test Potential Coronavirus Treatment
https://www.voanews.com/science-health/coronavirus-outbreak/global-trials-soon-test-potential-coronavirus-treatment

An American biotech company says it is working with Chinese authorities to determine whether the antiviral drug remdesivir may provide an effective treatment for victims of the fast-spreading coronavirus known as COVID-19. The Chinese researchers hope to have the answer by May 1.

Officials of Gilead Sciences, which invented remdesivir as a treatment for Ebola and another disease, told VOA the company has initiated two clinical trials among infected patients "to determine the safety and efficacy of remdesivir as a potential treatment for the coronavirus." ---CONTINUED---

Hat Tip to John West's Daily Big Threat Blog:

New US Guidelines Will Allow Faster Coronavirus Testing
https://www.voanews.com/science-health/coronavirus-outbreak/new-us-guidelines-will-allow-faster-coronavirus-testing

Federal regulators are allowing hospitals and other laboratories to develop their own tests for the coronavirus in an effort to relieve what critics say is a shortage of testing for the virus.

The urgency for testing is growing as health officials report several new coronavirus cases in the United States and the country's first death — a man in his 50s from Washington state.

The new policy unveiled on Saturday by the U.S. Food and Drug Administration (FDA), follows criticism that a lack of testing has allowed the virus to spread undetected. ---CONTINUED---

Hat Tip to FluTrackers:

Three Intravenous Vitamin C Research Studies Approved for Treating COVID-19

Three Intravenous Vitamin C Research Studies Approved for Treating COVID-19
http://orthomolecular.org

by Andrew W. Saul, Editor


(OMNS February 21, 2020) Intravenous vitamin C is already being employed in China against COVID-19 coronavirus. I am receiving regular updates because I am part of the Medical and Scientific Advisory Board to the International Intravenous Vitamin C China Epidemic Medical Support Team. Its director is Richard Z. Cheng, MD, PhD; associate director is Hong Zhang, PhD. Among other team members are Qi Chen, PhD (Associate Professor, Kansas University Medical School); Jeanne Drisko, MD (Professor, University of Kansas Medical School); Thomas E. Levy, MD, JD; and Atsuo Yanagisawa, MD, PhD. (Professor, Kyorin University, Tokyo). To read the treatment protocol information in English: http://orthomolecular.org/resources/omns/v16n07.shtml (Protocol in Chinese at http://www.doctoryourself.com/Corona...C_Protocol.pdf

Hat Tip to John West's Daily Big Threat Blog:

Coronavirus Vaccine Faces Bumpy Road From Lab to Jab
https://www.voanews.com/science-health/coronavirus-outbreak/coronavirus-vaccine-faces-bumpy-road-lab-jab

WASHINGTON - The first possible vaccine against coronavirus is on its way to human testing.

Just six weeks elapsed between when Chinese scientists released the sequence of the novel virus and when biotech company Moderna shipped its vaccine to the National Institute of Allergy and Infectious Disease to begin testing.

It's a record-breaking pace for vaccine development. Seveal other companies also are working to get their vaccines into clinical trials. ---CONTINUED---

Hat Tip to John West's Daily Big Threat Blog:

Fauci: Vaccine at least year away, as COVID-19 death toll rises to 9 in Seattle
http://www.cidrap.umn.edu/news-perspective/2020/03/fauci-vaccine-least-year-away-covid-19-death-toll-rises-9-seattle

Today US public health leaders addressed a Senate committee hearing and clarified the country's response to the growing COVID-19 outbreak that is now seeded in multiple communities.

"It will take at least a year to a year in a half to have a vaccine we can use," said National Institute of Allergy and Infectious Diseases (NIAID) director Anthony Fauci, MD. Though work on a novel coronavirus vaccine has been some of the fastest on record, Fauci said, he explained to senators that a vaccine candidate must be proven safe and efficacious in a multi-step trial process. ---CONTINUED---

Hat Tip to John West's Daily Big Threat Blog:

Coronavirus: Virologist Ian Lipkin's top tip for those who recover from Covid-19
https://www.indiatoday.in/india/story/virologist-lipkin-coronavirus-plasma-china-drugs-vaccine-treatment-1652457-2020-03-04

Virologist Dr W Ian Lipkin said that China is experimenting with plasma technology and if they reap successful results then it will prove to be a very effective counter measure to treat coronavirus.

Virologist Dr W Ian Lipkin, talking to India Today, said that those who have recovered from coronavirus should provide plasma to the plasma banks since it is effective in treating coronavirus.

The plasma, obtained from recovered patients, contains big volumes of antibodies for the deadly pathogen. From the donated blood, the plasma will be used to create antibodies to fight the deadly pathogens invading the victim's body. ---CONTINUED---

Hat Tip to FluTrackers:

First coronavirus vaccine trial in the US is recruiting volunteers
https://www.livescience.com/us-coronavirus-vaccine-trial-recruiting.html?fbclid=IwAR3psaPksuAJxHnq_B3K31gp4qztdslTLDfPC4O8TxGO57kDjAsihEFLHCs

Forty-five people will be enrolled in the preliminary safety trial of the new vaccine.

Researchers in Seattle have begun recruiting healthy volunteers to participate in a clinical trial for an experimental COVID-19 vaccine, according to news reports.

The vaccine, developed by the biotechnology company Moderna Therapeutics, was initially sent to the National Institute of Allergy and Infectious Diseases (NIAID) in Maryland on Feb. 24, according to The Wall Street Journal. The agency anticipates launching a clinical trial by the end of April and will sponsor the Kaiser Permanente Washington Health Research Institute to conduct the testing, NIAID Director Anthony Fauci told The Wall Street Journal. ---CONTINUED---

Hat Tip to John West's Daily Big Threat Blog:

China: Coronavirus Vaccine Could Be Ready for 'Emergency Use' in April
https://www.voanews.com/science-health/coronavirus-outbreak/china-coronavirus-vaccine-could-be-ready-emergency-use-april

Weeks after its scientists released the sequence of the coronavirus, China says the first vaccines could be in "emergency use" next month.

A top Chinese health official said Friday the country was moving full steam ahead to develop vaccines for the coronavirus, which has infected more than 100,000 people and killed upwards of 3,000 worldwide.

“According to our estimates, we are hopeful that in April some of the vaccines will enter clinical research or be of use in emergency situations,” said Zheng Zhongwei, director of the National Health Commission’s Science and Technology Development Center. ---CONTINUED---

Johns Hopkins develops its own coronavirus test
https://www.cbsnews.com/news/johns-hopkins-develops-its-own-coronavirus-test/

Doctors at Johns Hopkins Hospital in Baltimore have created their own coronavirus test, which they hope will help address the need for more testing for COVID-19.

Doctors at Hopkins said the country needs more widely available tests that return results more quickly. That's why they created a test on their own, reports CBS Baltimore.

Hopkins began using the test on Wednesday and by Thursday night, they were to have tested 50 samples. ---CONTINUED---

House passes coronavirus relief bill to provide free COVID-19 testing for everyone, paid emergency leave
https://abc7chicago.com/6012204/

The House of Representatives passed a bipartisan legislative package in response to the spread of coronavirus in the early hours of Saturday morning following intense negotiations between House Speaker Nancy Pelosi and the Trump administration.

The bill passed with broad, bipartisan support and a final tally of 363-40 with 40 Republicans voting against it and Independent Justin Amash of Michigan voting "present," reported CNN. ---CONTINUED---

Coronavirus vaccine trial is ready to administer it 2rst dose in Seattle
https://theconservativeopinion.com/coronavirus-vaccine-trial-is-ready-to-administer-its-first-dose-in-seattle/?fbclid=IwAR2blgRDOAmeS_6-vcAtPinO6aaINHWKySMuaGShVNGX7k0nSPpZ1Bc3xSA

Geekwire reports Seattle’s Kaiser Permanente Washington Health Research Institute plans give an experimental dose of coronavirus vaccine to the first participant in a clinical trial on Monday, The Associated Press quotes a government official as saying.

Kaiser Permanente’s Phase 1 clinical trial is the first U.S. study focusing on a potential vacc the virus that so far has killed at least 69 Americans and more than 6,500 elsewhere in the world. The test makes use of Moderna’s mRNA-1273 vaccine. ---CONTINUED---

Coronavirus Update: Vaccine Skips Important Animal Testing Phase, Straight To Human Trials
https://www.ibtimes.com/coronavirus-update-vaccine-skips-important-animal-testing-phase-straight-human-trials-2941208

KEY POINTS

--Human trials on the new COVID-19 vaccine began March 16 in the U.S.
--The human trials began even as animal trials are underway
--This unorthodox approach, which might compromise both the safety and efficacy of the new vaccine, is being questioned by biomedical ethicists ---CONTINUED---

China developing 9 potential vaccines in global race for coronavirus cure
https://www.scmp.com/news/china/society/article/3075722/china-developing-9-potential-vaccines-global-race-coronavirus

The race to develop a Covid-19
vaccine is on, with the United States already starting a clinical trial and China close behind.

On Tuesday, vaccine producer CanSino Biologics, in Tianjin in China’s northeast, said it was looking for volunteers to take part in a six-month clinical trial of a treatment it had developed jointly with the Academy of Military Medical Sciences.

“The vaccine does not contain infectious substances, is highly safe and stable, and requires only one inoculation,” the Hubei Centre for Disease Control and Prevention (CDC) said in its request for volunteers ---CONTINUED---

Irish company create coronavirus testing kit which can confirm infection in 15 minutes
https://www.irishpost.com/news/irish-company-create-coronavirus-testing-kit-can-confirm-infection-15-minutes-181738

AN IRISH company has invented a COVID-19 testing kit which can produce results in 15 minutes.

Assay Genie, a Reagent Genie brand invented by Colm Ryan and Seán Mac Fhearraigh, uses technology from pregnancy tests for rapid results, and has been tipped as being a "clinical weapon" against coronavirus.

As reported by The Irish Independent, the rapid testing kit measures one drop of blood, and while it is currently in the pilot phase, the creators believe it could be released in just seven days in order to tackle the spread of the virus. ---CONTINUED---

There are reports that the Malaria Vaccine works as an anti-viral against CoViD-19.
I have not looked at the reports, myself.
Got it third hand.

TRex2 wrote:There are reports that the Malaria Vaccine works as an anti-viral against CoViD-19.
I  have not looked at the reports, myself.
Got it third hand.

Here's the one you're thinking of TRex. There are some other drugs that are being tested also, one of them was for the treatment of ebola.


https://www.thedailybeast.com/anti-malaria-drug-to-be-made-available-to-coronavirus-patients-almost-immediately-trump-says